Study on middle cerebral artery stenosis or occlusion by CT perfusion and CT angiography with 64-detector row CT
GAO Yan; LI Kun-cheng*; DU Xiang-ying; LIU Jia-bin; YANG Yan-hui （Department of Radiology; Xuanwu Hospital; Capital University of Medical Sciences; Beijing 100053; China）;
【英文摘要】 Objective To evaluate the application value of combining cerebral CT perfusion (CTP) with CT angiography (CTA) of 64-detector row CT (MDCT) in cerebral ischemia caused by stenosis or occlusion of middle cerebral artery (MCA). Methods Thirty-seven patients with unilateral or bilateral stenosis or occlusion of MCA diagnosed by DSA and 10 normal adult volunteers were scanned by CT, and the unenhanced axial CT, CTP and CTA were performed. To discriminate the ischemic focus, the parameter maps of cerebral blood ...
【英文关键词】 Middle cerebral artery; Stenosis; Occlusion; CT perfusion; CT angiography;
64排螺旋CT脑灌注和CT血管成像在大脑中动脉狭窄或闭塞的应用
高艳; 李坤成; 杜祥颖; 刘佳宾; 杨延辉;
【摘要】 目的评价64排螺旋CT脑灌注(CTP)联合头颈部CT血管成像(CTA)检查对大脑中动脉(MCA)狭窄或闭塞所致脑缺血的临床应用价值。方法对37例经DSA诊断为单、双侧MCA狭窄或闭塞患者及10名正常成年志愿者分别进行螺旋CT头颅平扫、CTP和CTA检查。脑CTP检查获得脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)、达峰时间(TP)等参数值,判断脑缺血。结果按照脑CTP的MTT和TP图将脑灌注延迟表现分为三型:Ⅰ型病变仅累及MCA区,Ⅱ型病变仅累及分水岭区,Ⅲ型病变同时累及MCA和分水岭区。①在25例单侧MCA狭窄/闭塞患者中,4例CTP正常,17例脑CTP灌注延迟区为Ⅰ型,4例为Ⅲ型。②与正常对照组相比,12例双侧大脑中动脉重度狭窄患者的双侧MCA支配区均有MTT和TP延迟,CBF下降和症状侧CBV升高的异常改变,提示为双侧脑缺血。侧支循环能明显减少单侧MCA狭窄患者的症状侧的脑灌注损伤,但对双侧MCA重度狭窄和闭塞患者,无论有无侧支循环,双侧脑组织灌注损伤都很严重。结论脑CTP检查的MTT和TP图能敏感显示MCA重度狭窄或闭塞所致的脑灌注损伤,为脑缺血的诊断、治疗及预防脑梗死均具有重要价值...
【中文关键词】 大脑中动脉; 狭窄; 闭塞; CT灌注; CT血管成像;
【作者单位】 首都医科大学宣武医院医学影像学部放射科;
【文献出处】 中国医学影像技术 , Chinese Journal of Medical Imaging Technology, 编辑部邮箱 2006年 08期
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